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Long-term Antibiotics Ease Symptoms of Genetic Lung Disorder

Pathology & Lab Medicine - Medscape - Ven, 11/10/2019 - 19:23
Azithromycin improves symptoms for patients with primary ciliary dyskinesia, but researchers caution that vigilance must be maintained to prevent antibiotic resistance.
Medscape Medical News

'Landmark' Trial in Prostate Cancer With Mutations

Pathology & Lab Medicine - Medscape - Ven, 11/10/2019 - 19:23
Patients with metastatic prostate cancer carrying gene alterations show benefit from treatment with the PARP inhibitor olaparib in a 'landmark' trial.
Medscape Medical News

Brain Age Gap a Novel, Reliable Marker for Dementia Risk?

Pathology & Lab Medicine - Medscape - Gio, 10/10/2019 - 18:23
The gap between brain age, as estimated with MRI, and chronologic age may serve as a biomarker for dementia risk.
Medscape Medical News

5-Year Survival High for HIV+ to HIV+ Kidney Transplant

Pathology & Lab Medicine - Medscape - Gio, 10/10/2019 - 18:23
Study following kidney transplants from donors with HIV infection in South Africa to HIV positive recipients shows high rates of 5-year overall and graft survival.
Medscape Medical News

Aquaporins in Melanocytic and Nonmelanocytic Skin Tumors

Pathology & Lab Medicine - Medscape - Gio, 10/10/2019 - 18:23
This study investigated the role of aquaporin 1 and aquaporin 3 in the pathobiology of skin cancers. Might they have potential use as specific therapeutic and diagnostic targets?
American Journal of Clinical Pathology

Similar Benefits for Thrombectomy, Medical Management, in Mild Stroke

Pathology & Lab Medicine - Medscape - Gio, 10/10/2019 - 18:23
New analyses show no compelling evidence supporting either mechanical thrombectomy or medical management over the other for the treatment of mild stroke, setting the stage for a randomized trial.
Medscape Medical News

'Unprecedented' Results in Biliary Tract Cancer

Pathology & Lab Medicine - Medscape - Gio, 10/10/2019 - 18:23
Experts were impressed with results from a phase 3 study of a targeted agent in a subgroup of patients with cholangiocarcinoma with genetic mutations.
Medscape Medical News

Income Drop Hard on the Wallet and the Brain

Pathology & Lab Medicine - Medscape - Mer, 09/10/2019 - 17:23
Young adults who experience a drop in income experience poorer cognitive performance and exhibit lower brain volume on imaging in midlife, results of a large exploratory study showed.
Medscape Medical News

PRIORITY: Urine Test Spots Future Kidney Disease in Diabetes

Pathology & Lab Medicine - Medscape - Mar, 08/10/2019 - 16:23
Proteomic test identified patients with diabetes at high risk of kidney disease before they had detectable microalbuminuria. However, spironolactone did not mitigate the risk.
Medscape Medical News

'Chemical Burns' Seen as Possible Cause of Vaping Lung Damage

Pathology & Lab Medicine - Medscape - Mar, 08/10/2019 - 16:23
The recent surge of lung injuries among users of e-cigarette products appears to be caused by chemical toxicity and not from the accumulation of lipids in the lungs, researchers say.
Medscape Medical News

FDA Clears Architect Stat High-Sensitivity Troponin Test for MI

Pathology & Lab Medicine - Medscape - Mar, 08/10/2019 - 16:23
Abbott's Architect Stat troponin-I assay can identify myocardial infarction several hours sooner than standard troponin tests and improve diagnosis in women, the company says.
FDA Approvals

BPA Exposure in Pregnancy Can Affect Lung Health of Children

Pathology & Lab Medicine - Medscape - Mar, 08/10/2019 - 16:23
Children of women exposed to endocrine disruptors during pregnancy can suffer respiratory effects years later, adding to existing concerns about health risks related to bisphenol A (BPA).
Medscape Medical News

Yips May Affect More Athletes Than Previously Recognized

Pathology & Lab Medicine - Medscape - Lun, 07/10/2019 - 15:23
Yips, a focal task-specific dystonia, may be more prevalent among golfers than has previously been thought, a Dutch study has found. It affects athletes in other sports and activities as well.
Medscape Medical News

A1c Swings Tied to More Diabetes Complications Long Term

Pathology & Lab Medicine - Medscape - Lun, 07/10/2019 - 15:23
"We use the newer A1c variability score, and [we] followed a lifetime trajectory from new diagnosis [of type 2 diabetes] to the [adverse] event," says the senior author in explaining the research.
Medscape Medical News

The Eye in Dengue, an Aspect of Dengue Expanded Syndrome

Pathology & Lab Medicine - Medscape - Lun, 07/10/2019 - 15:23
This case report brings attention to the potential of eye involvement in dengue viral infection.
Journal of Medical Case Reports

NASH and Risk of Advanced Colorectal Neoplasm

Pathology & Lab Medicine - Medscape - Lun, 07/10/2019 - 15:23
This study indicates that the histological severity of NAFLD is strongly associated with advanced colorectal neoplasm.
Liver International

When Should Tumor Genomic Profiling Prompt Germline Testing?

Pathology & Lab Medicine - Medscape - Dom, 06/10/2019 - 14:23
These 5 steps will help clinicians determine whether patients with a pathogenic variant in a cancer susceptibility gene should be referred for germline testing.
Journal of Oncology Practice

Could 'Liquid Biopsy' Detect Vascular Complications in Diabetes?

Pathology & Lab Medicine - Medscape - Ven, 04/10/2019 - 12:23
Using an experimental assay to analyze just a few drops of blood appears to be predictive of vascular complications in diabetes; validation studies are next and a clinical trial is planned.
Medscape Medical News

Idarucizumab Reverses Dabigatran Regardless of Renal Function

Pathology & Lab Medicine - Medscape - Ven, 04/10/2019 - 12:23
In a RE-VERSE AD subgroup analysis, idarucizumab reversed the effects of dabigatran in more than 98% of patients, regardless of renal function.
Medscape Medical News
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