Pathology & Lab Medicine - Medscape

This study investigated the role of aquaporin 1 and aquaporin 3 in the pathobiology of skin cancers. Might they have potential use as specific therapeutic and diagnostic targets?
American Journal of Clinical Pathology

New analyses show no compelling evidence supporting either mechanical thrombectomy or medical management over the other for the treatment of mild stroke, setting the stage for a randomized trial.
Medscape Medical News

Experts were impressed with results from a phase 3 study of a targeted agent in a subgroup of patients with cholangiocarcinoma with genetic mutations.
Medscape Medical News

Young adults who experience a drop in income experience poorer cognitive performance and exhibit lower brain volume on imaging in midlife, results of a large exploratory study showed.
Medscape Medical News

Proteomic test identified patients with diabetes at high risk of kidney disease before they had detectable microalbuminuria. However, spironolactone did not mitigate the risk.
Medscape Medical News

The recent surge of lung injuries among users of e-cigarette products appears to be caused by chemical toxicity and not from the accumulation of lipids in the lungs, researchers say.
Medscape Medical News

Abbott's Architect Stat troponin-I assay can identify myocardial infarction several hours sooner than standard troponin tests and improve diagnosis in women, the company says.
FDA Approvals

Children of women exposed to endocrine disruptors during pregnancy can suffer respiratory effects years later, adding to existing concerns about health risks related to bisphenol A (BPA).
Medscape Medical News

Yips, a focal task-specific dystonia, may be more prevalent among golfers than has previously been thought, a Dutch study has found. It affects athletes in other sports and activities as well.
Medscape Medical News

"We use the newer A1c variability score, and [we] followed a lifetime trajectory from new diagnosis [of type 2 diabetes] to the [adverse] event," says the senior author in explaining the research.
Medscape Medical News

This case report brings attention to the potential of eye involvement in dengue viral infection.
Journal of Medical Case Reports

This study indicates that the histological severity of NAFLD is strongly associated with advanced colorectal neoplasm.
Liver International

These 5 steps will help clinicians determine whether patients with a pathogenic variant in a cancer susceptibility gene should be referred for germline testing.
Journal of Oncology Practice

Using an experimental assay to analyze just a few drops of blood appears to be predictive of vascular complications in diabetes; validation studies are next and a clinical trial is planned.
Medscape Medical News

In a RE-VERSE AD subgroup analysis, idarucizumab reversed the effects of dabigatran in more than 98% of patients, regardless of renal function.
Medscape Medical News

The final survival data from FLAURA establishes osimertinib as front-line therapy for patients with EGFR-mutated NSCLC. Give the best therapy first, experts say.
Medscape Medical News

Results from CheckMate 227 suggest that combination nivolumab and ipilimumab may eliminate the need for chemotherapy in advanced NSCLC, regardless of PD-L1 status.
Medscape Medical News

With the combination of ipilimumab and nivolumab, 50% of patients are still alive after 5 years, a survival rate remarkably higher than that seen with either agent alone.
Medscape Medical News

U.S. federal agents raided genetic testing laboratories, and 35 people were criminally charged in four states in a crackdown on genetic testing fraud that officials said on Friday caused $2.1 billion in losses to federal healthcare insurance programs.
Reuters Health Information

Three medical stories that we didn't cover, explained.
Medscape